| Anticancer activity : A potent inducer of phase II detoxication enzymes Antioxidant functions [Product name]: Sulforaphane (SFN) []:4-methylsulfinybutyl isothiocyanatel;Sulforafan;Sulforaphan;Sulphoraphane;(R)-sulforaphane;L-sulforaphane [Plant Source]:Broccoli seeds [Chemical name]: 1-isothiocyanato-4-(methyl-sulfinyl) butane [Structural formula]: C6H11S2NO [CAS Reg]:142825-10-3 [Molecular weight]: 177.29 [Specification]:Sulforaphane assay: 1%,10%,50%,95%(HPLC) In 1992 Hopkins scientists isolated sulforaphane from broccoli as the principal booster (inducer) of an elaborate network of protective (so-called phase II) enzymes that defend all aerobic cells against the constant damage of reactive oxygen (oxidative stress), DNA damaging chemicals (electrophiles), inflammation, and radiation. These damaging processes are the major causes of cancer and many chronic degenerative diseases.Sulforaphane is the most potent naturally occurring inducer of phase II enzymes,including quinone reductase and glutathione.Moreover,sulforaphane can reduce the incident of a number of forms of tumors and induce cell cycle arrest and apoptosis in various experimental models. Indirect antioxidants such as sulforaphane and other Phase II enzyme inducers are actually very efficient and rather versatile antioxidants for the following reasons: (a) unlike direct antioxidants, they are not consumed stoichiometrically while exerting antioxidant functions; (b) they have a longer duration of action and high cellular concentrations need not be maintained continuously since the induced enzymes have half-lives measured in days; (c) they support the functions of important naturally-occurring, direct-acting antioxidants such as the tocopherols and coenzymes Q; (d) they enhance the synthesis of glutathione, one of the most abundant intracellular direct antioxidants; and (d) they elevate enzymes that can cope with a wide variety of types of oxidants. [Storage]: Store in -20 & dry place, Keep away from strong light and heat
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